288 pp. per issue
6 x 9, illustrated
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Neural Computation

December 2006, Vol. 18, No. 12, Pages 2923-2927
(doi: 10.1162/neco.2006.18.12.2923)
© 2006 Massachusetts Institute of Technology
A Distributed Computing Tool for Generating Neural Simulation Databases
Article PDF (43.62 KB)

After developing a model neuron or network, it is important to systematically explore its behavior across a wide range of parameter values or experimental conditions, or both. However, compiling a very large set of simulation runs is challenging because it typically requires both access to and expertise with high-performance computing facilities. To lower the barrier for large-scale model analysis, we have developed NeuronPM, a client/server application that creates a “screen-saver” cluster for running simulations in NEURON (Hines & Carnevale, 1997). NeuronPM provides a user-friendly way to use existing computing resources to catalog the performance of a neural simulation across a wide range of parameter values and experimental conditions. The NeuronPM client is a Windows-based screen saver, and the NeuronPM server can be hosted on any Apache/PHP/MySQL server. During idle time, the client retrieves model files and work assignments from the server, invokes NEURON to run the simulation, and returns results to the server. Administrative panels make it simple to upload model files, define the parameters and conditions to vary, and then monitor client status and work progress. NeuronPM is open-source freeware and is available for download at It is a useful entry-level tool for systematically analyzing complex neuron and network simulations.