ISBN: 9780262298230 | 384 pp. | October 2011

How We Remember

Brain Mechanisms of Episodic Memory

Episodic memory proves essential for daily function, allowing us to remember where we parked the car, what time we walked the dog, or what a friend said earlier. In How We Remember, Michael Hasselmo draws on recent developments in neuroscience to present a new model describing the brain mechanisms for encoding and remembering such events as spatiotemporal trajectories. He reviews physiological breakthroughs on the regions implicated in episodic memory, including the discovery of grid cells, the cellular mechanisms of persistent spiking and resonant frequency, and the topographic coding of space and time. These discoveries inspire a theory for understanding the encoding and retrieval of episodic memory not just as discrete snapshots but as a dynamic replay of spatiotemporal trajectories, allowing us to "retrace our steps" to recover a memory.

In the main text of the book, he presents the model in narrative form, accessible to scholars and advanced undergraduates in many fields. In the appendix, he presents the material in a more quantitative style, providing mathematical descriptions appropriate for advanced undergraduates and graduate students in neuroscience or engineering.

Table of Contents

  1. Preface
  2. 1. Behavioral Dynamics of Episodic Memory
  3. 2. Neural Dynamics of Episodic Memory
  4. 3. Coding of Space and Time for Episodic Memory
  5. 4. Encoding and Retrieval of Episodic Trajectories
  6. 5. Linking Events and Episodes
  7. 6. Drug Effects on the Dynamics of Encoding and Retrieval
  8. 7. Drug Effects on the Dynamics of Encoding and Retrieval
  9. Appendix: Mathematical Models of Memory
  10. References
  11. Indexes
  12. Color Insert